Welcome to my website
On these pages you will find news and information about my scientific life.

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NEWS
 

October 2013

I have now joined the Ludwig Institute for Cancer Research at the University of Oxford as Senior Leadership Fellow / Group leader. We are applying for talented postdocs who are interested in Ubiquitin Signalling in Innate Immunity and Cancer. See our website for details about the post (link). Deadline for applications is 10th October.  

 

June 2013

Our paper on XIAP in XLP2 entitled "Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signaling" is published in EMBO molecular Medicine. (link) 

Our paper on the deubiquitinase OTULIN and its role regulating Met1-linked Ub and inflammation is published in Molecular Cell. (link)

Great news. I was awarded a Sapere Aude  Starting Grant from the Danish Research Council for Independent Research. (link)

 

May 2012

Our paper entitled "The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity" is published in Molecular Cell (link).

 

September 2011

Berthe Katrine Fiil joined the team as a postdoctoral fellow.

 

March 2011

Our review entitled "Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity" is published in Discovery Medicine (link PDF).   

 

January 2011

I have now joined the Novo Nordisk Foundation Center for Protein Research (CPR) at University of Copenhagen as associate professor in the Ubiquitin Signaling Group, headed by Niels Mailand and Simon Bekker-Jensen. Rune Damgaard who was working with me at BRIC has also joined the group and is now a PhD student. We will work on ubiquitin-mediated regulation of innate immune signaling as well as other aspects of ubiquitin signaling. 

 

July 2010

The review I have written with Pascal Meier, entitled "IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer" is now available online at Nature Reviews Cancer (link). We discuss the new developments on IAP proteins with focus on their role in NF-kappaB signalling, inflammation and cancer.

7th European Workshop on Cell Death (EWCD), which I organised together with Mads Daugaard (Apoptosis Department, Danish Cancer Society) was held at the Sankt Helene Centre in Tisvildeleje, Denmark from June 27th to July 2nd (link). The meeting turned out really well and it was great to meet with friends and colleagues from around the world to discuss science and extend collaborations. 

For those who are not familiar with EWCD meetings, I can highly recommend these meetings. They are fairly small meetings with roughly 150 participants and are held over 5 days every two years at different european locations. The overarching topic is understanding the biological processes that influence a cells decision to live or die and how deregulation of these processes contribute to human diseases. You can read more about EWCD meetings at our website (link).

 

June 2010

My student Rune Damgaard defended his master's thesis in flying colours - congratulations Rune!

 

May 2009

I received a 4-year career-development fellowship from the Danish Council for Independent Research – Natural Sciences (Steno Fellowship).